(Suc-LLVY)2R110

(Suc-LLVY)2R110 represents a specific peptide substrate commonly used in proteasome activity assays.

(Suc-LLVY)2:This portion refers to the peptide sequence Suc-Leu-Leu-Val-Tyr,which is a well-known substrate for the chymotrypsin-like activity of the proteasome. The "Suc" at the beginning denotes a succinyl group, which is often added to facilitate the binding of the peptide substrate to the proteasome.

R110: This part indicates that the substrate employs the fluorogenic dye Arginine-110 (R110) as a reporter group.When this peptide is cleaved by the proteasome, the fluorogenic dye is released, resulting in an increase in fluorescence that can be quantified to measure proteasome activity.

In summary,(Suc-LLVY)2R110 describes a peptide substrate containing the (Suc-LLVY) sequence and coupled with the R110 fluorophore, utilized in assays to monitor chymotrypsin-like activity of the proteasome.

msds of (Suc-LLVY)2R110